CELLULAR ADHESION TO CARBON NANOTUBES-ANCHORED OLIGONUCLEOTIDE: ELECTRO-CHEMICAL DETECTION

Abstract

In the study a new biosensor contained an oligonucleotide-carbon nanotubes-stearic acid monocrystalline clusters in its sensitive coating has been developed. The electrochemical characteristics of sensors with different coatings distinguishing by content of oligonucleotide and cerium ions have been measured. It was found that the presence of Ce in the coating leads to decrease of sensor capacity changes at measurements in mediums of different content. The oligonucleotides anchored in sensor coating attenuate cell nonantisense adhesion to sensor surface.