Antimutagens of dihydropyridine series – triggers of defense reactions of cell and organism against environmental mutagens

Abstract

Effective antimutagens (AM) suppressing spontaneous and chemically induced mutagenesis in germ- and somatic cells of animals were revealed among 1,4-dihydropyridine derivatives. Effects of these compounds were detail studied in different test-systems that made it possible to establish peculiarities and some mechanisms of their action