nthesis of Raspberry and Ginger Ketones by Nickel Boride-catalyzed ydrogenation of 4-Arylbut-3-en-2-ones

Abstract

Raspberry and ginger ketones 1 and 2 are well-known natural substances which became the ob-jects of both laboratory and industrial synthesis. Ow-ing to their intensive fragrance they found applications in perfumery, cosmetics and as food additives. Investigations of the biological activity of the pheno-lic compounds 1 and 2, in particular antioxidant and anti-inflammatory actions, cancer preven-tion and influence on the metabolic rate are still ongoing. In addition to that, the preparation of these simple structures with unusual properties is inter-esting as an educational process.