Some aspects of applying antimutagens as anticarcinogens

Abstract

Analysis of current data on antimutagens/anticarcinogens indicates that they affect practically all known molecular targets responsible for anticarcinogenesis. Antimutagens of 1,4-DHP series also show multiple mechanisms of action and seem to modulate expression of genes controlling cell response to genotoxic stress. These compounds are promising for prevention and inhibition of tumor growth at different carcinogenesis stages.