Пожалуйста, используйте этот идентификатор, чтобы цитировать или ссылаться на этот ресурс: http://elib.bspu.by/handle/doc/52653
Название: NANOPORE-PENETRATION SENSING EFFECTS FOR TARGET DNA SEQUENCING VIA IMPEDANCE DIFFERENCE BETWEEN ORGANOMETALLIC-COMPLEX-DECORATED CARBON NANOTUBES WITH TWISTED SINGLE-STRANDED OR DOUBLE-STRANDED DNA
Авторы: Babenko, A. S.
Grushevskaya, H. V.
Krylova, N.G.
Lipnevich, I. V.
Egorova, Valentina Petrovna
Chakukov, R. F.
Егорова, Валентина Петровна
Ключевые слова: double-stranded DNA
single-stranded DNA
multi-walled carbon nanotube (MWCNT)
nanopore-penetration sensing effect
Дата публикации: 2020
Серия/номер: NATO SCIENCE FOR PEACE AND SECURITY SERIES A: CHEMISTRY AND BIOLOGY;P. 247-258
Краткий осмотр (реферат): We offer a highly sensitive and reproducible dielectric-spectroscopy assay of deoxyribonucleic acid (DNA) sequence on a platform of quantum graphene-like structures arranged on nanoporous alumina to correctly identifying an infectious agent in a native double-stranded (ds) DNA. The hybridization of complementary target DNA with probe DNA in the sensor sensitive layer leads to penetration of the formed singlestranded (ss) target DNA into the underlayer nanoporous anodic alumina through the nanocavities of LB-film from organometallic complexes. This results in linking of MWCNT ends, shielding of Helmholtz double layer and following decrease of electrical capacitance of the sensor. The novel electrochemical impedimetric DNA sensor with selforganized multi-walled carbon nanotube (MWCNT) bundles decorated by organometallic complexes as transducer has been utilized to detect the viral DNA in the biological samples of patients with virus infection at DNA concentration as low as 1.0–1.3 ng/μL.
URI (Унифицированный идентификатор ресурса): http://elib.bspu.by/handle/doc/52653
Располагается в коллекциях:Научные публикации факультета естествознания



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